Sialylated Human Apolipoprotein E (apoEs) Is Preferentially Associated with Neuron-Enriched Cultures from APOE Transgenic Mice

Mice transgenic for human APOE2, E3, and E4 alleles express native 34-kDa human apoE and two sialylated apoE isoproteins with approximate molecular weights of 37 kDa (apoEs) and 39 kDa (apoEs2) in brain. These multiple apoE/apoEs/apoEs2band patterns on Western blot are also observed in human brain,...

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Bibliographic Details
Main Authors: Pu-Ting Xu, Donald Schmechel, Hui-Ling Qiu, Michael Herbstreith, Tracie Rothrock-Christian, Michele Eyster, Allen D. Roses, John R. Gilbert
Format: Article
Language:English
Published: Elsevier 1999-02-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996198902133