Interactions between the transmembrane domains of CD39: identification of interacting residues by yeast selection.

Rat CD39, a membrane-bound ectonucleoside triphosphate diphosphohydrolase that hydrolyzes extracellular nucleoside tri- and diphosphates, is anchored to the membrane by two transmembrane domains at the two ends of the molecule. The transmembrane domains are important for enzymatic activity, as mutan...

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Bibliographic Details
Main Authors: Guido Guidotti, Sari Paavilainen
Format: Article
Language:English
Published: ScienceOpen 2014-01-01
Series:ScienceOpen Research
Online Access:https://www.scienceopen.com/document?vid=3d21dcb9-cff4-4cfb-8176-fc70f367e6c4