Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase

Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase

Promoter recognition is a critical step in the initiation of transcription of DNA to RNA. Here, the authors describe a novel mechanism by which a phage-encoded RNA polymerase recognizes viral promoters containing deoxyuridines instead of thymidines.

Bibliographic Details
Main Authors: Alec Fraser, Maria L. Sokolova, Arina V. Drobysheva, Julia V. Gordeeva, Sergei Borukhov, John Jumper, Konstantin V. Severinov, Petr G. Leiman
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31214-6

Internet

https://doi.org/10.1038/s41467-022-31214-6

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