Complementary Experimental Methods to Obtain Thermodynamic Parameters of Protein Ligand Systems

In recent years, thermophoresis has emerged as a promising tool for quantifying biomolecular interactions. The underlying microscopic physical effect is still not understood, but often attributed to changes in the hydration layer once the binding occurs. To gain deeper insight, we investigate whethe...

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Bibliographic Details
Main Authors: Shilpa Mohanakumar, Namkyu Lee, Simone Wiegand
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/22/14198