Genotyping DNA pools on microarrays: Tackling the QTL problem of large samples and large numbers of SNPs

<p>Abstract</p> <p>Background</p> <p>Quantitative trait locus (QTL) theory predicts that genetic influence on complex traits involves multiple genes of small effect size. To detect QTL associations of small effect size, large samples and systematic screens of thousands...

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Bibliographic Details
Main Authors: Plomin Robert, Al-Chalabi Ammar, Hansen Valerie, Fernandes Cathy, Liu Lin, Butcher Lee M, Meaburn Emma, Craig Ian, Schalkwyk Leonard C
Format: Article
Language:English
Published: BMC 2005-04-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/6/52