Generation of panels of anti-idiotypic single-chain variable fragments mimicking Cry2Aa toxin using the chain shuffling technique

Generation of panels of anti-idiotypic single-chain variable fragments mimicking Cry2Aa toxin using the chain shuffling technique

Here, we firstly reported to generate panels of anti-idiotypic single-chain variable fragments (scFvs) of Bacillus thuringiensis Cry2Aa toxin by chain shuffling method. Light- and heavy-chain-shuffled libraries based on two parental clones were constructed. The signal of the light-chain-shuffled lib...

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Bibliographic Details
Main Authors: Yuan Liu, Manman Lin, Jiaxin Wu, Xiaodan Hu, Xiao Zhang, Chongxin Xu, Jianfeng Zhong, Yajing Xie, Cunzheng Zhang, Chuping Luo, Xianjin Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Food and Agricultural Immunology
Subjects:
chain shuffling
anti-idiotypic antibodies
single-chain variable fragments (scfvs)
cry2aa toxin
Online Access:http://dx.doi.org/10.1080/09540105.2018.1440535

Internet

http://dx.doi.org/10.1080/09540105.2018.1440535

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