Trop2-targeted therapy in breast cancer

Abstract Human trophoblastic cell surface antigen 2 (Trop2) is a glycoprotein, a cellular marker of trophoblastic and stem cells, and a calcium signaling transducer involved in several signaling pathways, leading to the proliferation, invasion, and metastasis of tumors. It is expressed at a low leve...

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Bibliographic Details
Main Authors: Yixuan Hu, Yinxing Zhu, Dan Qi, Cuiju Tang, Wenwen Zhang
Format: Article
Language:English
Published: BMC 2024-08-01
Series:Biomarker Research
Subjects:
Online Access:https://doi.org/10.1186/s40364-024-00633-6