In Vitro Cytotoxicity and In Vivo Antitumor Activity of Lipid Nanocapsules Loaded with Novel Pyridine Derivatives

In Vitro Cytotoxicity and In Vivo Antitumor Activity of Lipid Nanocapsules Loaded with Novel Pyridine Derivatives

This study demonstrates high drug-loading of novel pyridine derivatives (S1–S4) in lipid- and polymer-based core–shell nanocapsules (LPNCs) for boosting the anticancer efficiency and alleviating toxicity of these novel pyridine derivatives. The nanocapsules were fabricated using a nanoprecipitation...

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Bibliographic Details
Main Authors: Amr Selim Abu Lila, Mohammed Amran, Mohamed A. Tantawy, Ehssan H. Moglad, Shadeed Gad, Hadil Faris Alotaibi, Ahmad J. Obaidullah, El-Sayed Khafagy
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Pharmaceutics
Subjects:
antitumor activity
Ehrlich ascites carcinoma
MTT assay
nanocapsule
pyridine derivatives
Online Access:https://www.mdpi.com/1999-4923/15/6/1755

Internet

https://www.mdpi.com/1999-4923/15/6/1755

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