6-Shogaol attenuates natural aging-induced locomotive and cognitive declines through suppression of p75 neurotrophin receptor in vivo

The present study aimed to investigate the effect of 6-shogaol (6S) treatment on brain senescence. Mice were naturally aged until 25-month-old and treated with 10 mg/kg of 6S for a month. Behavioral tests were performed to measure locomotion and cognitive function. Neuronal damage, synaptic plastici...

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Bibliographic Details
Main Authors: Hyeyoon Eo, Jin Hee Kim, Hyeri Im, In Gyoung Ju, Eugene Huh, Rabin Pun, Dongyun Shin, Yunsook Lim, Myung Sook Oh
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624000276