Alpha-synuclein and tau are abundantly expressed in the ENS of the human appendix and monkey cecum.

Alpha-synuclein and tau are abundantly expressed in the ENS of the human appendix and monkey cecum.

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α-Synuclein (α-syn) proteinopathy in the neurons of the Enteric Nervous System (ENS) is proposed to have a critical role in Parkinson's disease (PD) onset and progression. Interestingly, the ENS of the human appendix harbors abundant α-syn and appendectomy has been linked to a decreased risk an...

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Bibliographic Details
Main Authors: Alexandra D Zinnen, Jonathan Vichich, Jeanette M Metzger, Julia C Gambardella, Viktoriya Bondarenko, Heather A Simmons, Marina E Emborg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0269190

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https://doi.org/10.1371/journal.pone.0269190

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