Can the HIV-1 splicing machinery be targeted for drug discovery?

Can the HIV-1 splicing machinery be targeted for drug discovery?

Zodwa Dlamini, Rodney Hull Research, Innovation & Engagements Portfolio, Mangosuthu University of Technology, Durban, South Africa Abstract: HIV-1 is able to express multiple protein types and isoforms from a single 9 kb mRNA transcript. These proteins are also expressed at particular stages...

Full description

Bibliographic Details
Main Authors: Dlamini Z, Hull R
Format: Article
Language:English
Published: Dove Medical Press 2017-03-01
Series:HIV/AIDS: Research and Palliative Care
Subjects:
Alternative splicing
exonic splicing enhancer
exonic specific silencer
HIV-1
SR proteins
hnRNP
Rev
Tat
Vpr
Online Access:https://www.dovepress.com/can-the-hiv-1-splicing-machinery-be-targeted-for-drug-discovery-peer-reviewed-article-HIV

Internet

https://www.dovepress.com/can-the-hiv-1-splicing-machinery-be-targeted-for-drug-discovery-peer-reviewed-article-HIV

Similar Items