Multi-Dose Intravenous Administration of Neutral and Cationic Liposomes in Mice: An Extensive Toxicity Study

Multi-Dose Intravenous Administration of Neutral and Cationic Liposomes in Mice: An Extensive Toxicity Study

Liposomes are widely used as delivery systems for therapeutic purposes. However, the toxicity associated with the multi-dose administration of these nanoparticles is not fully elucidated. Here, we evaluated the toxicity of the prolonged administration of liposomes composed of neutral or cationic pho...

Full description

Bibliographic Details
Main Authors: Stéphanie Andrade, Joana A. Loureiro, Santiago Ramirez, Celso S. G. Catumbela, Claudio Soto, Rodrigo Morales, Maria Carmo Pereira
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceuticals
Subjects:
lipid-based nanoparticles
nanocarrier
surface charge
delivery systems
chronic treatment
mice
Online Access:https://www.mdpi.com/1424-8247/15/6/761

Internet

https://www.mdpi.com/1424-8247/15/6/761

Similar Items