Infectious Bronchitis Virus Infection Increases Pathogenicity of H9N2 Avian Influenza Virus by Inducing Severe Inflammatory Response

Infectious bronchitis virus (IBV) and H9N2 avian influenza virus (AIV) are frequently identified in chickens with respiratory disease. However, the role and mechanism of IBV and H9N2 AIV co-infection remain largely unknown. Specific-pathogen-free (SPF) chickens were inoculated with IBV 2 days before...

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Bibliographic Details
Main Authors: Lingchen Kong, Renrong You, Dianchen Zhang, Qingli Yuan, Bin Xiang, Jianpeng Liang, Qiuyan Lin, Chan Ding, Ming Liao, Libin Chen, Tao Ren
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Veterinary Science
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.824179/full