TROP2 promotes PINK1-mediated mitophagy and apoptosis to accelerate the progression of senile chronic obstructive pulmonary disease by up-regulating DRP1 expression
Chronic obstructive pulmonary disease (COPD) is a chronic airway inflammatory disease characterised by irreversible airflow limitation. The elderly are a vulnerable population for developing COPD. With the growth of age, physiological degenerative changes occur in the thorax, bronchus, lung and vasc...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-06-01
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Series: | Experimental Gerontology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0531556524000834 |