Microbial Metabolites of 3-<i>n</i>-butylphthalide as Monoamine Oxidase A Inhibitors

Microbial Metabolites of 3-<i>n</i>-butylphthalide as Monoamine Oxidase A Inhibitors

Novel compounds with antidepressant activity via monoamine oxidase inhibition are being sought. Among these, derivatives of 3-<i>n</i>-butylphthalide, a neuroprotective lactone from <i>Apiaceae</i> plants, may be prominent candidates. This study aimed to obtain the oxidation...

Full description

Bibliographic Details
Main Authors: Joanna Gach, Joanna Grzelczyk, Tomasz Strzała, Filip Boratyński, Teresa Olejniczak
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
3-<i>n</i>-butylphthalide
monoamine oxidase A inhibitor
biotransformation
serotonin
fungal strains
Online Access:https://www.mdpi.com/1422-0067/24/13/10605

Internet

https://www.mdpi.com/1422-0067/24/13/10605

Similar Items