Inflammation‐induced cholestasis in cancer cachexia

Inflammation‐induced cholestasis in cancer cachexia

Abstract Background Cancer cachexia is a debilitating metabolic syndrome contributing to cancer death. Organs other than the muscle may contribute to the pathogenesis of cancer cachexia. This work explores new mechanisms underlying hepatic alterations in cancer cachexia. Methods We used transcriptom...

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Bibliographic Details
Main Authors: Morgane M. Thibaut, Martina Sboarina, Martin Roumain, Sarah A. Pötgens, Audrey M. Neyrinck, Florence Destrée, Justine Gillard, Isabelle A. Leclercq, Guillaume Dachy, Jean‐Baptiste Demoulin, Anne Tailleux, Sophie Lestavel, Marialetizia Rastelli, Amandine Everard, Patrice D. Cani, Paolo E. Porporato, Audrey Loumaye, Jean‐Paul Thissen, Giulio G. Muccioli, Nathalie M. Delzenne, Laure B. Bindels
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Liver
Hepatobiliary transport system
Bile acids
IL‐6
Cholestyramine
Online Access:https://doi.org/10.1002/jcsm.12652

Internet

https://doi.org/10.1002/jcsm.12652

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