Proteasome inhibition as a therapeutic target for the fungal pathogen Cryptococcus neoformans

ABSTRACT The current therapeutic challenges for treating fungal diseases demand new approaches and new drugs. A promising strategy involves combination therapy with agents of distinct mechanisms of action to increase fungicidal activity and limit the impact of mutations leading to resistance. In thi...

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Bibliographic Details
Main Authors: Mélissa Caza, Daniel Assis Santos, Elizabeth Burden, Anna Brisland, Guanggan Hu, James W. Kronstad
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01904-23