Double Duty: Complete Pathologic Response of Two Colonic Primaries with Mosaicism of a Novel <i>MLH1</i> Mutation to Neoadjuvant Pembrolizumab
We present a fascinating case of a 57-year-old male with a novel mutation in MLH1 (<i>MLH1:c.1288G > T, p.(Glu430*)</i>), who presented with two synchronous colonic tumours, initially deemed unresectable, and experienced a complete pathological response on neoadjuvant pembrolizumab. E...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-10-01
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| Series: | Current Oncology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1718-7729/30/10/653 |