Detection of cancer stem cells by EMT-specific biomarker-based peptide ligands

Abstract The occurrence of epithelial-mesenchymal transition (EMT) within tumors, which enables invasion and metastasis, is linked to cancer stem cells (CSCs) with drug and radiation resistance. We used two specific peptides, F7 and SP peptides, to detect EMT derived cells or CSCs. Human tongue squa...

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Bibliographic Details
Main Authors: Yi-An Chen, Cheau-Ling Ho, Min-Tzu Ku, Luen Hwu, Cheng-Hsiu Lu, Sain-Jhih Chiu, Wen-Yi Chang, Ren-Shyan Liu
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-01138-0