Toll-like receptor 5 tunes hepatic and pancreatic stellate cells activation

Objective Stellate cells are responsible for liver and pancreas fibrosis and strictly correlate with tumourigenesis. Although their activation is reversible, an exacerbated signalling triggers chronic fibrosis. Toll-like receptors (TLRs) modulate stellate cells transition. TLR5 transduces the signal...

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Bibliographic Details
Main Authors: Malte Buchholz, Detlef Schuppan, Pietro Di Fazio, Sophia Mielke, Isabell T Böhm, Sami Matrood, Thaddeus Wissniowski
Format: Article
Language:English
Published: BMJ Publishing Group 2023-08-01
Series:BMJ Open Gastroenterology
Online Access:https://bmjopengastro.bmj.com/content/10/1/e001148.full