Mycophenolate Improves Brain–Gut Axis Inducing Remodeling of Gut Microbiota in DOCA-Salt Hypertensive Rats

Mycophenolate Improves Brain–Gut Axis Inducing Remodeling of Gut Microbiota in DOCA-Salt Hypertensive Rats

Microbiota is involved in the host blood pressure (BP) regulation. The immunosuppressive drug mofetil mycophenolate (MMF) ameliorates hypertension. The present study analyzed whether MMF improves dysbiosis in mineralocorticoid-induced hypertension. Male Wistar rats were assigned to three groups: unt...

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Bibliographic Details
Main Authors: Iñaki Robles-Vera, Néstor de la Visitación, Manuel Sánchez, Manuel Gómez-Guzmán, Rosario Jiménez, Javier Moleón, Cristina González-Correa, Miguel Romero, Tao Yang, Mohan K. Raizada, Marta Toral, Juan Duarte
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antioxidants
Subjects:
mycophenolate
gut dysbiosis
hypertension
oxidative stress
inflammation
(deoxycorticosterone acetate) DOCA-salt model
Online Access:https://www.mdpi.com/2076-3921/9/12/1199

Internet

https://www.mdpi.com/2076-3921/9/12/1199

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