Transcriptomic profiling of calcified aortic valves in clonal hematopoiesis of indeterminate potential carriers

Abstract Clonal hematopoiesis of indeterminate potential (CHIP) is characterized by the presence of clones of mutated blood cells without overt blood diseases. In the last few years, it has emerged that CHIP is associated with atherosclerosis and coronary calcification and that it is an independent...

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Bibliographic Details
Main Authors: Francesco Vieceli Dalla Sega, Domenico Palumbo, Francesca Fortini, Ylenia D’Agostino, Paolo Cimaglia, Luisa Marracino, Paolo Severi, Oriana Strianese, Roberta Tarallo, Giovanni Nassa, Giorgio Giurato, Giovanni Pecoraro, Serena Caglioni, Elisa Mikus, Alberto Albertini, Gianluca Campo, Roberto Ferrari, Paola Rizzo, Alessandro Weisz, Francesca Rizzo
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24130-8