Transgenic Mice Overexpressing PG1 Display Corneal Opacity and Severe Inflammation in the Eye

Transgenic Mice Overexpressing PG1 Display Corneal Opacity and Severe Inflammation in the Eye

Antimicrobial peptides (AMPs) are of interest as alternatives to antibiotics or immunomodulators. We generated and characterized the phenotypes of transgenic mice overexpressing protegrin 1 (PG1), a potent porcine cathelicidin. No obvious differences were observed between PG1 transgenic and wild-typ...

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Bibliographic Details
Main Authors: Min-Kyeung Choi, Minh Thong Le, Hye-Sun Cho, Juyoung Lee, Hyoim Jeon, Se-Yeoun Cha, Manheum Na, Taehoon Chun, Jin-Hoi Kim, Hyuk Song, Chankyu Park
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
protegrin
antimicrobial peptide
cathelicidin
transgenic mice
corneal opacity
Online Access:https://www.mdpi.com/1422-0067/22/4/1586

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https://www.mdpi.com/1422-0067/22/4/1586

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