Single-cell RNA-seq identified novel genes involved in primordial follicle formation

Single-cell RNA-seq identified novel genes involved in primordial follicle formation

IntroductionThe number of primordial follicles (PFs) in mammals determines the ovarian reserve, and impairment of primordial follicle formation (PFF) will cause premature ovarian insufficiency (POI).MethodsBy analyzing public single-cell RNA sequencing performed during PFF on mice and human ovaries,...

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Bibliographic Details
Main Authors: Hang-Jing Tan, Zi-Heng Deng, Hui Shen, Hong-Wen Deng, Hong-Mei Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Endocrinology
Subjects:
primordial follicle formation
single cell RNA sequencing
in vitro ovarian culture
premature ovarian insufficiency
whole exome sequencing
whole genome sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1285667/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1285667/full

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