Single-cell RNA-seq identified novel genes involved in primordial follicle formation

Single-cell RNA-seq identified novel genes involved in primordial follicle formation

IntroductionThe number of primordial follicles (PFs) in mammals determines the ovarian reserve, and impairment of primordial follicle formation (PFF) will cause premature ovarian insufficiency (POI).MethodsBy analyzing public single-cell RNA sequencing performed during PFF on mice and human ovaries,...

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Bibliographic Details
Main Authors:	Hang-Jing Tan, Zi-Heng Deng, Hui Shen, Hong-Wen Deng, Hong-Mei Xiao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-12-01
Series:	Frontiers in Endocrinology
Subjects:	primordial follicle formation single cell RNA sequencing in vitro ovarian culture premature ovarian insufficiency whole exome sequencing whole genome sequencing
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1285667/full

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