A fluorescence imaging technique suggests that sweat leakage in the epidermis contributes to the pathomechanism of palmoplantar pustulosis

Abstract Sweat is an essential protection system for the body, but its failure can result in pathologic conditions, including several skin diseases, such as palmoplantar pustulosis (PPP). As reduced intraepidermal E-cadherin expression in skin lesions was confirmed in PPP skin lesions, a role for in...

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Bibliographic Details
Main Authors: Kazuki Yatsuzuka, Ryosuke Kawakami, Yosuke Niko, Teruko Tsuda, Kenji Kameda, Nobushige Kohri, Satoshi Yoshida, Ken Shiraishi, Jun Muto, Hideki Mori, Yasuhiro Fujisawa, Takeshi Imamura, Masamoto Murakami
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50875-x