Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems

Type I R-M systems help establish the prokaryotic DNA methylation landscape and provide protection against invasive DNA. Here, the authors report on detailed structural and molecular mechanisms of a non-canonical type I R-M methyltransferase.

Bibliographic Details
Main Authors: Jingpeng Zhu, Yina Gao, Yong Wang, Qi Zhan, Han Feng, Xiu Luo, Peipei Li, Songqing Liu, Hai Hou, Pu Gao
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34085-z