Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems
Type I R-M systems help establish the prokaryotic DNA methylation landscape and provide protection against invasive DNA. Here, the authors report on detailed structural and molecular mechanisms of a non-canonical type I R-M methyltransferase.
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-34085-z |
| _version_ | 1828316776679604224 |
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| author | Jingpeng Zhu Yina Gao Yong Wang Qi Zhan Han Feng Xiu Luo Peipei Li Songqing Liu Hai Hou Pu Gao |
| author_facet | Jingpeng Zhu Yina Gao Yong Wang Qi Zhan Han Feng Xiu Luo Peipei Li Songqing Liu Hai Hou Pu Gao |
| author_sort | Jingpeng Zhu |
| collection | DOAJ |
| description | Type I R-M systems help establish the prokaryotic DNA methylation landscape and provide protection against invasive DNA. Here, the authors report on detailed structural and molecular mechanisms of a non-canonical type I R-M methyltransferase. |
| first_indexed | 2024-04-13T17:19:29Z |
| format | Article |
| id | doaj.art-723346eabbf74cf9bff69354b7e389f5 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-13T17:19:29Z |
| publishDate | 2022-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-723346eabbf74cf9bff69354b7e389f52022-12-22T02:38:02ZengNature PortfolioNature Communications2041-17232022-10-0113111210.1038/s41467-022-34085-zMolecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systemsJingpeng Zhu0Yina Gao1Yong Wang2Qi Zhan3Han Feng4Xiu Luo5Peipei Li6Songqing Liu7Hai Hou8Pu Gao9CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of SciencesCAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of SciencesCAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of SciencesCAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of SciencesCAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of SciencesCAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of SciencesCAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of SciencesCAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of SciencesInstitute of Medical Research, Northwestern Polytechnical UniversityCAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of SciencesType I R-M systems help establish the prokaryotic DNA methylation landscape and provide protection against invasive DNA. Here, the authors report on detailed structural and molecular mechanisms of a non-canonical type I R-M methyltransferase.https://doi.org/10.1038/s41467-022-34085-z |
| spellingShingle | Jingpeng Zhu Yina Gao Yong Wang Qi Zhan Han Feng Xiu Luo Peipei Li Songqing Liu Hai Hou Pu Gao Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems Nature Communications |
| title | Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems |
| title_full | Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems |
| title_fullStr | Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems |
| title_full_unstemmed | Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems |
| title_short | Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems |
| title_sort | molecular insights into dna recognition and methylation by non canonical type i restriction modification systems |
| url | https://doi.org/10.1038/s41467-022-34085-z |
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