Neurovirulence of Usutu virus in human fetal organotypic brain slice cultures partially resembles Zika and West Nile virus

Neurovirulence of Usutu virus in human fetal organotypic brain slice cultures partially resembles Zika and West Nile virus

Abstract Usutu (USUV), West Nile (WNV), and Zika virus (ZIKV) are neurotropic arthropod-borne viruses (arboviruses) that cause severe neurological disease in humans. However, USUV-associated neurological disease is rare, suggesting a block in entry to or infection of the brain. We determined the rep...

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Bibliographic Details
Main Authors: Eleanor M. Marshall, Ahmad S. Rashidi, Michiel van Gent, Barry Rockx, Georges M. G. M. Verjans
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Scientific Reports
Subjects:
Flavivirus
Usutu virus
West Nile virus
Zika virus
Neurotropism & ex vivo brain model
Online Access:https://doi.org/10.1038/s41598-024-71050-w

Internet

https://doi.org/10.1038/s41598-024-71050-w

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