Doxorubicin Conjugated γ-Globulin Functionalised Gold Nanoparticles: A pH-Responsive Bioinspired Nanoconjugate Approach for Advanced Chemotherapeutics

Doxorubicin Conjugated γ-Globulin Functionalised Gold Nanoparticles: A pH-Responsive Bioinspired Nanoconjugate Approach for Advanced Chemotherapeutics

Developing successful nanomedicine hinges on regulating nanoparticle surface interactions within biological systems, particularly in intravenous nanotherapeutics. We harnessed the surface interactions of gold nanoparticles (AuNPs) with serum proteins, incorporating a γ-globulin (γG) hard surface cor...

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Bibliographic Details
Main Authors: Gaurav Chauhan, Vianni Chopra, América García Alvarado, Jocelyn Alexandra Gómez Siono, Marc J. Madou, Sergio Omar Martinez-Chapa, Manish M. Kulkarni
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pharmaceutics
Subjects:
gold nanoparticles
hard protein corona
γ-Globulin
doxorubicin
nanobioconjugate
pH responsive
Online Access:https://www.mdpi.com/1999-4923/16/2/208

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https://www.mdpi.com/1999-4923/16/2/208

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