Gq neuromodulation of BLA parvalbumin interneurons induces burst firing and mediates fear-associated network and behavioral state transition in mice

The authors study mechanisms underlying neuromodulatory control of transitions between brain and behavioral states. They identify a mechanism whereby modulation of Gq activity in basolateral amygdala parvalbumin interneurons mediates the transition to a fear-associated network and behavioral state.

Bibliographic Details
Main Authors: Xin Fu, Eric Teboul, Grant L. Weiss, Pantelis Antonoudiou, Chandrashekhar D. Borkar, Jonathan P. Fadok, Jamie Maguire, Jeffrey G. Tasker
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-28928-y