ROS is a master regulator of in vitro matriptase activation

Matriptase is a type II transmembrane serine protease that is widely expressed in normal epithelial cells and epithelial cancers. Studies have shown that regulation of matriptase expression and activation becomes deranged in several cancers and is associated with poor disease-free survival. Although...

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Bibliographic Details
Main Authors: Darius O. Gaymon, Robert Barndt, Hillary Stires, Rebecca B. Riggins, Michael. D. Johnson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886240/?tool=EBI