BMI1 induces ubiquitination and protein degradation of Nod‐like receptor family CARD domain containing 5 and suppresses human leukocyte antigen class I expression to induce immune escape in non‐small cell lung cancer
Abstract The Nod‐like receptor (NLR) family CARD domain containing 5 (NLRC5) has been reported as an activator of human leukocyte antigen (HLA) class I that is responsible for immune activity in cancer treatment. This work focuses on the role of BMI1 proto‐oncogene (BMI1) in the NLRC5‐HLA class I ax...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-12-01
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Series: | Kaohsiung Journal of Medical Sciences |
Subjects: | |
Online Access: | https://doi.org/10.1002/kjm2.12602 |