Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.

Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.

Recent GWAS studies focused on uncovering novel genetic loci related to AD have revealed associations with variants near CLU, CR1, PICALM and BIN1. In this study, we conducted a genome-wide association study in an independent set of 1034 cases and 1186 controls using the Illumina genotyping platform...

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Bibliographic Details
Main Authors: Xiaolan Hu, Eve Pickering, Yingxue Cathy Liu, Stephanie Hall, Helene Fournier, Elyse Katz, Bryan Dechairo, Sally John, Paul Van Eerdewegh, Holly Soares, Alzheimer's Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3044719?pdf=render

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http://europepmc.org/articles/PMC3044719?pdf=render

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