The C5a-C5aR1 complement axis is essential for neutrophil recruitment to draining lymph nodes via high endothelial venules in cutaneous leishmaniasis

The C5a-C5aR1 complement axis is essential for neutrophil recruitment to draining lymph nodes via high endothelial venules in cutaneous leishmaniasis

Summary: Neutrophils are specialized innate immune cells known for their ability to fight pathogens. However, the mechanisms of neutrophil trafficking to lymph nodes are not fully clear. Using a murine model of dermal infection with Leishmania parasites, we observe a transient neutrophil influx in d...

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Bibliographic Details
Main Authors: Borja Prat-Luri, Christopher Neal, Katiuska Passelli, Emma Ganga, Jonas Amore, Luan Firmino-Cruz, Tatiana V. Petrova, Andreas J. Müller, Fabienne Tacchini-Cottier
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722005411

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http://www.sciencedirect.com/science/article/pii/S2211124722005411

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