By Regulating Mitochondrial Ca2+-Uptake UCP2 Modulates Intracellular Ca2+.

By Regulating Mitochondrial Ca2+-Uptake UCP2 Modulates Intracellular Ca2+.

The possible role of UCP2 in modulating mitochondrial Ca2+-uptake (mCa2+-uptake) via the mitochondrial calcium uniporter (MCU) is highly controversial.Thus, we analyzed mCa2+-uptake in isolated cardiac mitochondria, MCU single-channel activity in cardiac mitoplasts, dual Ca2+-transients from mitocho...

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Detalles Bibliográficos
Main Authors: Lukas Jaroslaw Motloch, Robert Larbig, Tina Gebing, Sara Reda, Astrid Schwaiger, Johannes Leitner, Martin Wolny, Lars Eckardt, Uta C Hoppe
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC4746117?pdf=render

Internet

http://europepmc.org/articles/PMC4746117?pdf=render

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