The evolutionary origin of the Runx/CBFbeta transcription factors – Studies of the most basal metazoans

<p>Abstract</p> <p>Background</p> <p>Members of the Runx family of transcriptional regulators, which bind DNA as heterodimers with CBFβ, are known to play critical roles in embryonic development in many triploblastic animals such as mammals and insects. They are known t...

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Bibliographic Details
Main Authors: Groner Yoram, Levanon Ditsa, Marlow Heather, Reitzel Adam M, Shigesada Katsuya, Eisenstein Miriam, Sher Daniel, Sullivan James C, Finnerty John R, Gat Uri
Format: Article
Language:English
Published: BMC 2008-08-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/8/228