Different Spatial and Temporal Roles of Monocytes and Monocyte-Derived Cells in the Pathogenesis of an Imiquimod Induced Lupus Model

Different Spatial and Temporal Roles of Monocytes and Monocyte-Derived Cells in the Pathogenesis of an Imiquimod Induced Lupus Model

Mounting evidence indicates the importance of aberrant Toll-like receptor 7 (TLR7) signaling in the pathogenesis of systemic lupus erythematosus (SLE). However, the mechanism of disease progression remains unclear. An imiquimod (IMQ)-induced lupus model was used to analyze the lupus mechanism relate...

Full description

Bibliographic Details
Main Authors: Atsushi Nomura, Miho Mizuno, Daisuke Noto, Aki Aoyama, Taiga Kuga, Goh Murayama, Asako Chiba, Sachiko Miyake
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
classical monocytes
non-classical monocytes
imiquimod
toll-like receptor 7
resident macrophages
systemic lupus erythematosus
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.764557/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.764557/full

Similar Items