Podosomes and Invadopodia: Related structures with Common Protein Components that May Promote Breast Cancer Cellular Invasion

A rate-limiting step in breast cancer progression is acquisition of the invasive phenotype, which can precede metastasis. Expression of cell-surface proteases at the leading edge of a migrating cell provides cells with a mechanism to cross tissue barriers. A newly appreciated mechanism that may be r...

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Bibliographic Details
Main Authors: Daniel C. Flynn, YoungJin Cho, Deanne Vincent, Jess M. Cunnick
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Breast Cancer: Basic and Clinical Research
Online Access:https://doi.org/10.4137/BCBCR.S789