Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated malaria and prevalence of Pfk13 and Pfmdr1 polymorphisms after a decade of using artemisinin-based combination therapy in mainland Tanzania

Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated malaria and prevalence of Pfk13 and Pfmdr1 polymorphisms after a decade of using artemisinin-based combination therapy in mainland Tanzania

Abstract Background The World Health Organization recommends regular therapeutic efficacy studies (TES) to monitor the performance of first and second-line anti-malarials. In 2016, efficacy and safety of artemether-lumefantrine (AL) for the treatment of uncomplicated falciparum malaria were assessed...

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Bibliographic Details
Main Authors: Deus S. Ishengoma, Celine I. Mandara, Filbert Francis, Eldin Talundzic, Naomi W. Lucchi, Billy Ngasala, Abdunoor M. Kabanywanyi, Muhidin K. Mahende, Erasmus Kamugisha, Reginald A. Kavishe, Florida Muro, Ally Mohamed, Renata Mandike, Sigsbert Mkude, Frank Chacky, Lynn Paxton, George Greer, Chonge A. Kitojo, Ritha Njau, Troy Martin, Meera Venkatesan, Marian Warsame, Eric S. Halsey, Venkatachalam Udhayakumar
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Malaria Journal
Subjects:
Efficacy
Safety
Artemether-lumefantrine
Falciparum malaria
Tanzania
Online Access:http://link.springer.com/article/10.1186/s12936-019-2730-1

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http://link.springer.com/article/10.1186/s12936-019-2730-1

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