Impact of Consolidative Unrelated Cord Blood Transplantation on Clinical Outcomes of Patients With Relapsed/Refractory Acute B Lymphoblastic Leukemia Entering Remission Following CD19 Chimeric Antigen Receptor T Cells

Impact of Consolidative Unrelated Cord Blood Transplantation on Clinical Outcomes of Patients With Relapsed/Refractory Acute B Lymphoblastic Leukemia Entering Remission Following CD19 Chimeric Antigen Receptor T Cells

BackgroundWhile chimeric antigen receptor (CAR)-T cell therapy is becoming widely used in hematological malignancies with remarkable remission rate, their high recurrence remains an obstacle to overcome. The role of consolidative transplantation following CAR-T cell-mediated remission remains contro...

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Bibliographic Details
Main Authors: Qianwen Xu, Lei Xue, Furun An, Hui Xu, Li Wang, Liangquan Geng, Xuhan Zhang, Kaidi Song, Wen Yao, Xiang Wan, Juan Tong, Huilan Liu, Xin Liu, Xiaoyu Zhu, Zhimin Zhai, Zimin Sun, Xingbing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
chimeric antigen receptor (CAR)
unrelated cord blood transplantation
acute B lymphoblastic leukemia
CD19
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.879030/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.879030/full

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