Biological and Clinicopathological Significance of Cripto-1 Expression in the Progression of Human ESCC

Background: Human Cripto-1, a member of the EGF-CFC family, is involved in embryonic development, embryonic stem cell maintenance, and tumor progression. It also participates in multiple cell signaling pathways including Wnt, Notch, and TGF-β. Remarkably, it is expressed in cancer stem cell (CSC) co...

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Main Authors: Reihaneh Alsadat Mahmoudian, Mohammad Reza Abbaszadegan, Mohammad Mahdi Forghanifard, Meysam Moghbeli, Faezeh Moghbeli, Jamshidkhan Chamani, Mehran Gholamin
Format: Article
Language:English
Published: Varastegan Institute for Medical Sciences 2017-05-01
Series:Reports of Biochemistry and Molecular Biology
Subjects:
Online Access:http://rbmb.net/article-1-106-en.pdf