Neonatal Isoflurane Does Not Affect Sleep Architecture and Minimally Alters Neuronal Beta Oscillations in Adolescent Rats

Neonatal Isoflurane Does Not Affect Sleep Architecture and Minimally Alters Neuronal Beta Oscillations in Adolescent Rats

General anesthetics are neurotoxic to the developing rodent and primate brains leading to neurocognitive and socio-affective impairment later in life. In addition, sleep patterns are important predictors of cognitive outcomes. Yet, little is known about how anesthetics affect sleep-wake behaviors an...

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Bibliographic Details
Main Authors: Francesca M. Manzella, Bethany F. Gulvezan, Stefan Maksimovic, Nemanja Useinovic, Yogendra H. Raol, Srdjan M. Joksimovic, Vesna Jevtovic-Todorovic, Slobodan M. Todorovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
anesthesia
neurotoxicity
sleep
EEG
beta oscillations
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2021.703859/full

Internet

https://www.frontiersin.org/articles/10.3389/fnbeh.2021.703859/full

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