Reduced aquaporin-1 transcript expression in colorectal carcinoma is associated with promoter hypermethylation

Reduced aquaporin-1 transcript expression in colorectal carcinoma is associated with promoter hypermethylation

Aquaporin-1 (AQP1) is a homo-tetrameric transmembrane protein that facilitates rapid movement of water and ions across cell membranes. The clinical significance of AQP1 expression in colorectal carcinoma (CRC) is controversial. The aim of this study was to investigate the prognostic significance of...

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Bibliographic Details
Main Authors: Eric Smith, Yoko Tomita, Helen M. Palethorpe, Stuart Howell, Maryam Nakhjavani, Amanda R. Townsend, Timothy J. Price, Joanne P. Young, Jennifer E. Hardingham
Format: Article
Language:English
Published: Taylor & Francis Group 2019-02-01
Series:Epigenetics
Subjects:
colorectal cancer
aquaporin-1 (aqp1)
expression
dna methylation
prognosis
Online Access:http://dx.doi.org/10.1080/15592294.2019.1580112

Internet

http://dx.doi.org/10.1080/15592294.2019.1580112

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