Application of 5-ALA Fluorescence-guided Resection in Patients Suffering From High-grade Gliomas: A Report of 30 Consecutive Cases and a Literature Review

Background and Aim: The extent of resection seems a solid prognostic factor in patients with high-grade gliomas (HGGs). When administered orally, 5-aminolevulinic acid (5-ALA) is exclusively converted into protoporphyrin IX (PPIX) by malignant cells and detects, identifying contrast-enhancing glial...

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Bibliographic Details
Main Authors: Mohammad Mirahmadi Eraghi, Seyed Amir Hossein Javadi, Martin Mortazavi, Seyed Morsal Mosallami Aghili, Seyed Khalil Pestei
Format: Article
Language:English
Published: Guilan University of Medical Sciences 2022-08-01
Series:Iranian Journal of Neurosurgery
Subjects:
Online Access:http://irjns.org/article-1-308-en.pdf