NLRP3 inflammasome regulates astrocyte transformation in brain injury induced by chronic intermittent hypoxia

NLRP3 inflammasome regulates astrocyte transformation in brain injury induced by chronic intermittent hypoxia

Abstract Background Obstructive sleep apnea (OSA) is mainly characterized by sleep fragmentation and chronic intermittent hypoxia (CIH), the latter one being associated with multiple organ injury. Recently, OSA-induced cognition dysfunction has received extensive attention from scholars. Astrocytes...

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Bibliographic Details
Main Authors: Ningning She, Yewen Shi, Yani Feng, Lina Ma, Yuqi Yuan, Yitong Zhang, Zine Cao, Xi Chen, Bingjie Zhao, Haiqin Liu, Xiaoyong Ren
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Neuroscience
Subjects:
NLRP3
Caspase-1
ASC
IL-1β
Astrocytes
CIH Animal models
Online Access:https://doi.org/10.1186/s12868-022-00756-2

Internet

https://doi.org/10.1186/s12868-022-00756-2

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