GART Functions as a Novel Methyltransferase in the RUVBL1/β‐Catenin Signaling Pathway to Promote Tumor Stemness in Colorectal Cancer

GART Functions as a Novel Methyltransferase in the RUVBL1/β‐Catenin Signaling Pathway to Promote Tumor Stemness in Colorectal Cancer

Abstract Tumor stemness is associated with the recurrence and incurability of colorectal cancer (CRC), which lacks effective therapeutic targets and drugs. Glycinamide ribonucleotide transformylase (GART) fulfills an important role in numerous types of malignancies. The present study aims to identif...

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Bibliographic Details
Main Authors: Chao Tang, Mengying Ke, Xichao Yu, Shanliang Sun, Xian Luo, Xin Liu, Yanyan Zhou, Ze Wang, Xing Cui, Chunyan Gu, Ye Yang
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Advanced Science
Subjects:
cancer stem cells
colorectal cancer
glycinamide ribonucleotide transformylase 
pemetrexed
RUVBL1/β‐catenin axis
Online Access:https://doi.org/10.1002/advs.202301264

Internet

https://doi.org/10.1002/advs.202301264

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