Pre-analytical sample handling effects on tear fluid protein levels

Abstract Tear fluid is emerging as a source of non-invasive biomarkers, both for ocular and systemic conditions. Accurate quantification of tear proteins can be improved by standardizing methods to collect and process tear fluid. The aim of this study was to determine sample handling factors that ma...

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Bibliographic Details
Main Authors: Marlies Gijs, Sinthuja Arumugam, Nienke van de Sande, Carroll A. B. Webers, Swaminathan Sethu, Arkasubhra Ghosh, Rohit Shetty, Jelle Vehof, Rudy M. M. A. Nuijts
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28363-z