Effect of Pd<sub>2</sub>Spermine on Mice Brain-Liver Axis Metabolism Assessed by NMR Metabolomics

Effect of Pd<sub>2</sub>Spermine on Mice Brain-Liver Axis Metabolism Assessed by NMR Metabolomics

Cisplatin (cDDP)-based chemotherapy is often limited by severe deleterious effects (nephrotoxicity, hepatotoxicity and neurotoxicity). The polynuclear palladium(II) compound Pd<sub>2</sub>Spermine (Pd<sub>2</sub>Spm) has emerged as a potential alternative drug, with favorable...

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Bibliographic Details
Main Authors: Tatiana J. Carneiro, Martin Vojtek, Salomé Gonçalves-Monteiro, Ana L. M. Batista de Carvalho, Maria Paula M. Marques, Carmen Diniz, Ana M. Gil
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
palladium(II)
platinum(II)
spermine
Pd<sub>2</sub>Spm
cisplatin
mice
Online Access:https://www.mdpi.com/1422-0067/23/22/13773

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https://www.mdpi.com/1422-0067/23/22/13773

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