Plasma corticosterone activates SGK1 and induces morphological changes in oligodendrocytes in corpus callosum.

Plasma corticosterone activates SGK1 and induces morphological changes in oligodendrocytes in corpus callosum.

Repeated stressful events are known to be associated with onset of depression. Further, stress activates the hypothalamic-pituitary-adrenocortical (HPA) system by elevating plasma cortisol levels. However, little is known about the related downstream molecular pathway. In this study, by using repeat...

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Main Authors: Shingo Miyata, Yoshihisa Koyama, Kana Takemoto, Keiko Yoshikawa, Toshiko Ishikawa, Manabu Taniguchi, Kiyoshi Inoue, Miwa Aoki, Osamu Hori, Taiichi Katayama, Masaya Tohyama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3104997?pdf=render

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http://europepmc.org/articles/PMC3104997?pdf=render

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